TrailBio® Valproic Acid (Sodium Salt)

$115.00

Potent HDAC inhibitor

  • Directly inhibits HDACs, driving histone hyperacetylation.
  • Used to study epigenetic regulation, neuronal development and autophagy.
  • Known to affect GABA levels and subsequent neurotransmission.
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Description

Technical Information & Resources

Supporting Publications

Phiel et al. (2001), J Biol Chem

  • Shows VPA directly inhibits HDAC, causes histone hyperacetylation in cultured cells and activates Wnt-dependent gene expression.

Lu et al. (2017), Neurochem Res

  • Demonstrates that VPA promotes neuronal differentiation and neurite outgrowth in cultured neural stem cells.

Huangfu et al. (2008), Nat Biotechnol

  • Shows VPA enables reprogramming of primary human fibroblasts with only Oct4 and Sox2, without c-Myc or Klf4.

Additional information

Chemical Name

2-propyl-, sodium salt (1:1)

CAS Number

1069-66-5

Purity

≥98%

Formula

C8H15NaO2

Molecular Weight

166.19 g/mol

Usage

For research use only

Storage (Solid)

4 °C for up to 2 years

Storage (Solution)

-80 °C for up to 6 months or -20 °C for up to 1 month, store sealed away
from moisture

Form

Powder

Shipping

Ambient temperature