TrailBio^® Hydrocortisone

Rhen & Cidlowski (2005), N Engl J Med 

• Reviews how glucocorticoids act through the glucocorticoid receptor on multiple signaling pathways to resolve inflammation, including repression of pro-inflammatory transcription factors. 

Lapillonne et al. (2010), Haematologica 

• Reports the first complete differentiation of human iPSCs into enucleated red blood cells, using a two-step, animal-protein-free, cytokine-based protocol. 

Förster et al. (2008), J Physiol 

• In human brain microvascular endothelial cells (hCMEC/D3), glucocorticoid treatment raised occludin and claudin-5 expression and increased barrier tightness more than threefold, while hydrocortisone protected against TNFα-induced barrier breakdown.