TrailBio® Retinoic Acid

$125.00

Nuclear Retinoid Receptor (RAR/RXR) Agonist

  • RAR/RXR nuclear receptor agonist that drives transcription via retinoic acid response elements (RAREs).
  • Regulates Hox gene expression to guide iPSC exit from pluripotency toward neuroectodermal fate.
  • Used in iPSC neural induction, embryoid body/organoid patterning, and directed differentiation protocols.
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Description

Technical Information & Resources

Supporting Publications

Giguere et al. (1987), Nature

Petkovich et al. (1987), Nature

  • These two papers, published back-to-back, first cloned and identified RAR as a ligand-activated transcription factor homologous to steroid/thyroid hormone receptors, establishing the RAR mechanism.

Horschitz et al. (2015), Stem Cell Research

  • RA preconditioning during early neural induction of hiPSCs, showing increased neuronal yield and longer axon outgrowth.

Additional information

Chemical Name

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid

CAS Number

302-79-4

Purity

≥98%

Formula

C20H28O2

Molecular Weight

300.44 g/mol

Usage

For research use only

Storage (Solid)

-20 °C for up to 3 years, protect from moisture and light

Storage (Solution)

-80 °C for up to 6 months or -20 °C for up to 1 month; protect from light

Form

Powder

Shipping

Ambient temperature