Webinar

Presenter:​

Jan Jensen, PhD ​
Founder, CEO & CSO, Trailhead Biosystems

Webinar Summary:

Pluripotent stem cells (PSC) are a promising source of in vitro generated specialized cells for disease modeling, drug discovery, and cell therapy. However, large-scale cell differentiation is necessary to achieve this potential. Trailhead Biosystems utilizes the High-Dimensional Design of Experiments (HD-DoE™) platform to revolutionize cellular research. This method allows us to efficiently explore and optimize cell growth and differentiation processes. By analyzing multiple variables together, HD-DoE accelerates the development of precisely differentiated stem cells and cell therapy products. It’s a cornerstone of our approach to advancing regenerative medicine and personalized healthcare, enabling us to make significant breakthroughs in biotechnology. Trailhead Biosystems conducts experiments to understand cell fate behavior in response to various input signals, leading to the extraction of specific cell fate induction recipes. This approach allows for control of cell lineages effectively and avoids conflicting inputs that drive alternative fates. The proprietary software tools and robotic experiments allow for speed, precision, and scalability. The focus is on empirical data and unbiased determination of critical process parameters, building all our protocols from scratch. ​

In this webinar you will learn about: ​

• How Trailhead Biosystems has innovated large-scale cell differentiation with the HD-DoE™ platform ​
• How rigorous science and in-depth QC can result in superior cellular data and results ​
• How Trailhead Biosystems used iPSCs generated via REPROCELL’s StemRNA Reprogramming Technology to optimize their differentiation process of cells to support future clinical work.