TrailBio^® Thiazovivin

Lin et al. (2009), Nature Methods

• Foundational paper that describes a three-compound reprogramming platform using Thiazovivin, SB431542 (Cat No. TB46416), and PD0325901 (Cat No. TB27940) that improved human fibroblast iPSC generation efficiency by more than 200-fold and enhanced survival after trypsinization.

Xu et al. (2010), PNAS

• Study identifying Thiazovivin as a small molecule that increases hESC survival after dissociation while maintaining pluripotency, supporting its use in pluripotent stem cell survival and self-renewal workflows.

Valamehr et al. (2012), Scientific Reports

• Study shows a cocktail containing Thiazovivin supported feeder-free, single-cell hiPSC culture by improving viability, plating efficiency, pluripotency maintenance, and reprogramming performance.