Trailhead Biosystems, Inc. offers committed endothelial cells from iPSC cultures. These cells offer a physiologically relevant and reliable opportunity for investigations of vascular pathology, tissue engineering and drug development. The endothelium comprises the interface between tissues and blood lymph. They orchestrate crucial processes such as coagulation, permeability, tissue regeneration and immune responses. Endothelial cell dysfunction is a key player in cardiovascular diseases such as hypertension and atherosclerosis. Additionally, dysfunctional endothelial cells have been implicated in nonvascular pathologies including neurodegeneration and chronic inflammatory conditions.