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Pre-Released Products

TrailBio™ Insulin-Producing Islet-like Clusters

Human iPSC-derived islet-like cells

TrailBio™ Insulin-Producing Islet-like Clusters are highly characterized cells that resemble an immature pancreatic beta cell state. These cells enable the screening of compounds that modulate beta cell function and survival, supporting drug development for diabetes and models for other conditions involving beta cell dysfunction or loss.
TrailBio™ Insulin-Producing Islet-like Clusters are naturally differentiated from human iPSCs using the HD-DoE™ technology platform, meaning scalability is built-in.
Upon thawing (day 1), cells are ready for experimentation and express markers typical of mature beta cells. By simply maintaining cells in culture, they retain their characteristic morphology and marker expression.

Product Information

Starting Material: Human iPSCs
Format: Cryopreserved aggregates
Donor Information: Male
Karyotype: Normal
Source Cell: CD34+ cord blood
Shipping info: Dry ice
Quality Control: Sterility, bulk RNA-seq, flow cytometry, ICC, insulin content, GSIS
Differentiation method: Directed Differentiation
Seeding Compatibility: T75 Flask/6 well plate
User Storage: LN2
Recommended seeding density: vial per T75 flask or vial per 6-well plate
Protocol use: TrailBio™ cells are for research use only

The Trailhead Advantage

Defined

Human beta cells initially display a typical precursor cell-like morphology. When implanted, these immature islet-like clusters can mature in vivo into insulin-producing cells.

Non-Edited

These cells maintain their unmodified genome as they are directly differentiated.

Easy to use

Cryopreserved aggregates arrive ready to be used upon revival. Simple suspension culture protocol.

Custom iPSC Differentiation

Do you need differentiated cells but need to model specific diseases or require proprietary iPSC lines? Trailhead Biosystems’ Custom Differentiation Service can help! 

With our Custom Differentiation Services, you can:  

  • Send us your disease-specific cells or iPSC lines  
  • Leverage our proprietary protocols for precise differentiation
  • Obtain highly relevant, disease-specific cell types  

Our expert team will work closely with you to develop customized cellular models that recapitulate your disease of interest.  

Take your research to new heights with unparalleled access to disease-relevant cell types, meticulously differentiated to meet your unique requirements. 

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